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post in: Lifestyle, News Date:08 Oct 2017, 18:35 views:4400
How do people inherit glucose-6-phosphate dehydrogenase deficiency?
This condition is inherited in an X-linked recessive pattern. The gene associated with this condition is located on the X chromosome, which is one of the two sex chromosomes. In males (who have only one X chromosome one altered copy of the gene in each cell is sufficient to army cause the condition.
In females (who have two X chromosomes a mutation would have to occur in both copies of the gene to cause the disorder.
Because it is unlikely that females will have two altered copies of this gene, males are affected by X-linked recessive disorders much more frequently than females.
A striking characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons. What other names do people use for glucose-6-phosphate dehydrogenase deficiency? Deficiency of glucose-6-phosphate dehydrogenase, g6PDD, g6PD Deficiency, medically reviewed by Edward Spence, MD; American Board of Pediatrics and American Board of Medical Genetics with subspecialties in Clinical Genetics, Clinical Biochemical Genetics, Clinical Molecular Genetics.
Source: Genetics Home Reference. Reviewed on 4/15/2014, references, medically reviewed by Edward Spence, MD; American Board of Pediatrics and American Board of Medical Genetics with subspecialties in Clinical Genetics, Clinical Biochemical Genetics, Clinical Molecular Genetics.
G6PD deficiency can cause haemolysis and anaemia. Learn what this has to do with blood, the problems it can cause, and what medicines you should avoid. Learn about G6PD deficiency, a disorder caused by an abnormal X-chromosome gene, which causes hemolytic anemia.