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post in: Lifestyle Date:22 Aug 2017, 20:17 views:660
What are asthma treatment options? Are there home remedies for asthma?allergy allergy
As per widely used guidelines, the treatment goals for asthma are to: adequately control symptoms, minimize the risk of future exacerbations, maintain normal lung function, maintain normal activity levels, and use the least amount of medication possible with the least amount of potential side effects. Inhaled corticosteroids (ICS) are the most effective anti-inflammatory agents available for the chronic treatment of asthma and are first-line therapy per most asthma guidelines. It is well recognized that ICS are very effective in decreasing the risk of asthma exacerbations.
Furthermore, the combination of a long-acting bronchodilator (laba) and an ICS has a significant additional beneficial effect on improving asthma control. The most commonly used asthma medications include the following: Short-acting bronchodilators (albuterol Proventil, Ventolin, ProAir, ProAir RespiClick, Maxair, Xopenex ) provide quick relief and can be used in conjunction for exercise-induced symptoms.
Inhaled steroids ( budesonide, pulmicort Turbuhaler, Pulmicort Respules, fluticasone Flovent, Arnuity Ellipta, beclomethasone. Qvar, mometasone, asmanex, ciclesonide Alvesco, flunisolide, aerobid, Aerospan) are first-line anti-inflammatory therapy.
Long-acting bronchodilators ( salmeterol, serevent, formoterol. Foradil, vilanterol) can be added to ICS as additive therapy. Labas should never be used alone for the treatment of asthma.
Leukotriene modifiers ( montelukast, singulair, zafirlukast, accolate, zileuton, zyflo ) can also serve as anti-inflammatory agents. Anticholinergic agents (ipratropium, atrovent, Atrovent HFA, tiotropium Spiriva, umeclidinium Incruse Ellipta) can help decrease sputum production. Anti-IgE treatment ( omalizumab Xolair ) can be used in allergic asthma.
Anti-IL5 treatment (mepolizumab Nucala, reslizumab Cinqair) can be used in eosinophilic asthma. Chromones ( cromolyn Intal, Opticrom, Gastrocrom, nedocromil Alocril ) stabilize mast cells (allergic cells) but are rarely used in clinical practice. Theophylline ( Respbid, Slo-Bid, Theo-24 ) also helps with bronchodilation (opening the airways) but is rarely used in clinical practice due to an unfavorable side-effect profile.
Systemic steroids ( prednisone Deltasone, Liquid Pred, prednisolone Flo-Pred, Pediapred, Orapred, Orapred ODT, methylprednisolone Medrol, Depo-Medrol, Solu-Medrol, dexamethasone DexPak) are potent anti-inflammatory agents that are routinely used to treat asthma exacerbations but pose numerous unwanted side effects if used repeatedly or chronically. Numerous additional monoclonal antibodies are also currently being studied and will likely be available within the next couple of years. Immunotherapy or allergy shots have been shown to decrease medication reliance in allergic asthma.