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post in: Lifestyle, Health Date:11 Oct 2017, 13:52 views:2997
Bronchial Thermoplasty, delivered by the Alair System, is a treatment for severe asthma approved by the FDA in 2010 involving the delivery of controlled, therapeutic radiofrequency energy to the airway wall, thus heating the tissue dose and reducing the amount of smooth muscle present in the. 1, this treatment has been shown to result in acute epithelial destruction with regeneration observed in the epithelium, blood vessels, mucosa and nerves.
However, airway smooth muscle has demonstrated almost no capacity for regeneration, instead being replaced by connective tissue. 2, the treatment has been shown to be safe and effective over at least five years.
3, contents, the Procedure edit, animation of bronchial thermoplasty catheter use, a full course of bronchial thermoplasty treatment 4 includes three separate bronchoscopic procedures: one for the each lower lobe of the lung and another for both upper lobes.
Each outpatient procedure is performed approximately three weeks apart. Under sedation, a catheter inside a bronchoscope a thin, flexible tube-like instrument introduced through the patients nose or mouth, and into their lungsdelivers thermal energy into the airways. The patient is monitored after the procedure and usually returns home that day or early the next day.
The catheter delivers a series of 10-second temperature controlled bursts of radio frequency energy which heat the lining of the lungs to 65 herbal degrees Celsius. It is this heat that destroys some of the muscle tissue which constricts during an asthma attack, reducing the number and severity of exacerbations. In a double-blind, randomized, sham-controlled clinical study of bronchial thermoplasty, 5 adults with severe asthma that were treated with bronchial thermoplasty had improved asthma-related quality of life out to a year compared to the control (sham-treated) patients.
Additionally, when compared to control patients, patients treated with bronchial thermoplasty also experienced the following significant benefits: 32 reduction in asthma attacks 84 reduction in emergency room visits for respiratory symptoms 66 reduction in days lost from work, school, or other daily activities due. Reduction in asthma attacks, ER visits, and hospitalizations for respiratory symptoms are maintained to at least 5 years.
3, these benefits were observed during clinical studies where patients continued to take their standard maintenance asthma medications which included combinations of inhaled corticosteroids and long-acting bronchodilators. Risks of Procedure edit In the period immediately following the bronchial thermoplasty procedure, there was an expected transient increase in the frequency and worsening of respiratory-related symptoms.