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post in: News Date:12 Nov 2017, 08:31 views:2837
Previous research has suggested that a low level of vitamin D may raise the difference risk of asthma, dermatitis, and certain allergies. A new study looks at the asthma genetic data available to see if genetic variations support the conclusions of previous research. Some previous studies have associated low circulating levels of vitamin D with an increased risk of asthma, atopic dermatitis, and higher levels of total immunoglobulin E (IgE).
A team of researchers - led.
Brent Richards, of the McGill University and the Lady Davis Institute at the Jewish General Hospital, both in Montreal, Canada - set out to determine whether or not there exacerbation is a genetic background to these alleged correlations.
As the authors of the new study explain, atopy is a term that refers to a predisposition to allergic diseases including asthma and atopic dermatitis, or eczema. Atopy usually presents itself with elevated. IgE levels - a type of immunoglobulin that serves to protect against parasitic infections.
The studies that correlated low vitamin, d with increased IgE levels and associated disease risk were observational, the authors of the new research point out. Given that vitamin D deficiency affects over 40 percent of the population of the United States and is easy to remedy with supplements, the alleged correlation between low vitamin D and allergic disorders could be a matter of public health, the authors write. In this context,.
Richards and team decided to investigate the genetic data available.
The results were published in the journal, pLOS Medicine.
The team examined the single nucleotide polymorphisms (SNPs) of more than 100,000 people from existing large-scale studies, such as the sunlight Consortium, the Canadian Multicentre Osteoporosis Study, and the eagle Eczema Consortium. SNPs are the most common form of genetic variation found in people's DNA.