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Get rights and content, under an Elsevier user license, keywords general asthma wards guideline adherence septic shock. Recommended articles, citing articles (0 copyright 2012 Published by Elsevier (Singapore) Pte Ltd.
1Intensive Care, Department of Medicine, King Abdulaziz Hospital,.O. Box 2477, Al-Ahsa, Saudi Arabia 2Department of Emergency Medicine, King Abdulaziz Hospital, Al-Ahsa, Saudi Arabia 3Infectious Diseases/Department of Medicine, King Abdulaziz Hospital, Al-Ahsa, Saudi Arabia. Copyright 2012 Javed.
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To assess the effect of improved compliance with 6-hour sepsis resuscitation bundle on mortality in patients with severe sepsis and septic shock.
A quasi-experimental prospective study was conducted at a 10-bedded combined medical and surgical intensive care unit. The historical benesleep group included all consecutive patients with severe sepsis and septic shock admitted from January 2008 to March 2009. Intervention included evidence-based written sepsis pathway, antibiotic recommendations, and an educational e post-intervention group included all consecutive patients admitted from July 2009 to June 2011.
The primary outcome measures were the overall compliance to seven 6-hour sepsis resuscitation bundle elements and 30-day hospital mortality. There were 99 patients in the historical group and 199 in the post-intervention group. The baseline patients' characteristics were similar.
Overall compliance to all seven sepsis resuscitation bundle elements in historical group was.1 95 confidence interval (CI.111.3 which improved after intervention.6 (95 CI,.930.1. The overall compliance to 6-hour sepsis resuscitation bundle elements was associated with improved survival odds ratio (OR.8 (95 CI,.215.1; ). 30-day hospital mortality reduced from.3 in the historical group.1 asthma in the intervention group;.
Improvement in compliance to 6-hour sepsis resuscitation bundle was associated with a reduction in 30-day hospital mortality.