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post in: Products, News Date:08 Oct 2017, 19:02 views:829
Class Summary, these agents provide no bronchodilatory effect but are useful in controlling the underlying inflammation of allergic asthma. Flunisolide (AeroBid, AeroBid-M flunisolide is considered a third-line agent that decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing capillary permeability.
It does not depress the hypothalamus. Beclomethasone dipropionate (Beconase AQ, qvar beclomethasone dipropionate inhibits bronchoconstriction mechanisms and produces direct smooth muscle relaxation.
It may decrease number and activity of inflammatory cells, in turn decreasing airway hyperresponsiveness.
As with other agents in this class, beclomethasone dipropionate is also considered a third-line agent. Ciclesonide is an aerosol inhaled corticosteroid indicated for maintenance treatment of asthma as prophylactic therapy. It is not indicated for relief of acute bronchospasm.
Corticosteroids have wide range of effects on multiple cell types (eg, mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (eg, histamines, eicosanoids, leukotrienes, cytokines) involved in inflammation. Individual patients experience a variable time to onset and degree of symptom relief. Fluticasone (Flovent HFA, Flovent Diskus fluticasone inhibits bronchoconstriction mechanisms, produces direct smooth muscle relaxation, and decreases the number and activity of inflammatory cells, in turn decreasing airway hyper-responsiveness.
It also has vasoconstrictive activity. Budesonide (Pulmicort Flexhaler budesonide inhibits bronchoconstriction mechanisms, produces direct smooth muscle relaxation, and decreases the number and activity of inflammatory cells, in turn decreasing airway hyperresponsiveness.
It has extremely potent vasoconstrictive and anti-inflammatory activity. It alters level of inflammation in airways by inhibiting multiple types of inflammatory cells and decreasing the production of cytokines and other mediators.
It also decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability).
Asthma inhalers or bronchodilators used care prior to exercise can control and prevent exercise-induced asthma symptoms. The preferred asthma medications are.