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Grevillea robyn gordon allergy and asthma

post in: Video Date:08 Oct 2017, 16:37 views:4692

Grevillea robyn gordon allergy and asthma

Introduction, plants are living organisms belonging to the kingdom of Plantae that includes at least 300000 species considering trees, herbs, bushes, grasses, vines, ferns, mosses and green algae.

Although most plants are harmless to skin contact or ingestion, mild to serious adverse events are also well-recognized. Several cutaneous adverse reactions to plants such as non-immunological contact urticaria, irritant contact dermatitis, allergic contact dermatitis, photo-toxic contact dermatitis and photo-allergic contact dermatitis have been reported. Allergic contact dermatitis is one of the most frequent cutaneous side effects in individuals exposed to plants.

The study of the pathogenic mechanisms implicated in the development of allergic contact dermatitis to plants (acdp) may be challenging.

The large number of species, the diversity of chemical compounds that they contain and the simultaneous contact with more than one allergen may explain nhlbi these difficulties. A wide range of plants and plant allergens responsible for ACD have been identified and the different contact dermatitis triggers have often been classified according botanical asthma criteria. These classifications are useful but do not allow predicting cross-reactivity among different species or families and require a botanical knowledge often cumbersome to physicians, dermatologists and allergologists.

A possible classification of plant contact dermatitis according to the main chemical structures acting as allergens could be useful and may allow preventing future exposures to the responsible agent or its cross-reacting compounds that could be present in different species or families. Our main objective is to review plant induced allergic contact dermatitis from the chemical point of view. The responsible plants are classified according their chemical allergens.

Several families of chemical sensitizers causing different types of contact and photo-contact allergic dermatitis are reviewed (. Plant Contact Dermatitis Classified by its Chemical Responsible Allergenic The -methylene-butyrolactones are part of a large and varied group of bioactive natural products widely present in plants. They have an,-unsaturated carbonyl system which allows the formation of covalent adducts with nucleophilic residues on diverse biomolecules which explains their high chemical reactivity.

Most of them are of the sesquiterpene type (15 carbon atoms molecule) guidelines with an -methylene group directed exocyclically to the -lactone ring. They are classified into six main groups of sesquiterpene lactone (SQL) structures: guaianolide, pseudoguaianolide, xanthonolide, ermophilanolide, eudesmanolide and germacranolide (.

 

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